Changes in Saliva Composition before and after Use of Mouthwash Containing Green Tea Extract
박정은, 장종화, 황수연, 김다희, 조자원,
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박정은 ( Park Jung-Eun ) - Dankook University College of Health Science Department of Dental Hygiene
장종화 ( Jang Jong-Hwa ) - Dankook University College of Health Science Department of Dental Hygiene
황수연 ( Hwang Su-Yeon ) - Korea University Graduate School Department of Public Health Sciences
김다희 ( Kim Da-Hui ) - Dankook University College of Health Science Department of Dental Hygiene
조자원 ( Cho Ja-Won ) - Dankook University College of Dentistry Department of Preventive Dentistry
Abstract
Objective: The goal of this study was to evaluate the efficacy of green tea extract (GTE) in reducing oral bacteria by analysis of saliva composition before and after using mouthwash containing GTE.
Methods: This study measured organic acids (lactate, acetate, propionate, formate, butyrate, pyruvate, valerate) found in the saliva of 15 healthy adults before and 1, 2, and 4 weeks after use of GTE mouthwash. A Dionex ion chromatography system was used for analysis. During the mobile phase, NaOH 100 mM was applied through isocratic elution.
Results: Changes in saliva composition compared to a control after the use of mouthwash containing GTE, included an increase in lactate during the first and second week followed by a decrease of 0.48 mM (82.74%) in the fourth week. Acetate slightly increased by 0.03 mM (0.46%) compared to the control. Propionate, formate, butyrate, and pyruvate increased 0.11-1.55 mM after four weeks compared with the control. Valerate was not detected.
Conclusion: Seven organic acids were compared. Only lactate decreased after use of the GTE mouthwash. Therefore, the GTE mouthwash in this study has the potential to inhibit the growth of some oral bacteria.
키워드
Camellia sinensis; lactic acid; oral health; saliva
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